Products for Research Use Only
RegisterLogin

Lon-TK

CAT: 0931-T203042-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T203042-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation
Bioactivity
Lon-TK is a glycolysis inhibitor of LTB, linked with a linker conjugate. LTB is an intelligent responsive prodrug, comprised of Lonidamine (Lon) and a PD-L1 inhibitor (BMS-1), which are connected through a thioketal linkage. It effectively inhibits glycolytic metabolism in tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK holds potential for use in photodynamic-enhanced immunotherapy research.
Molecular Formula
C24H28Cl2N2O3S2
Molecular Weight
527.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T210621-01TK-685
T88236-01TK-642
TP2088ω-Agatoxin TK
T211274-01TK-684
T60713-01TK-129
T205705-01EGFR-TK-IN-5
T88884-01EGFR-TK-IN-4
T209533-01EGFR-TK-IN-2
T11582-01HSV-TK substrate
T32856Lon 954

Alternative Products

CatalogName
HY-169436Lon-TK
ARC0953TK
MBS1026902Recombinant Lon protease (lon), partial
GTR17971930Lon Antibody
HY-173571TK-685
HY-P1079ω-Agatoxin TK
MBS8512170-01TK Antibody
MBS5803436TK-129

Popular Products