TK-642

• Target:

  Phosphatase

• Related Pathways:

  Metabolism

• Bioactivity:

  TK-642 is a potent and selective SHP2 inhibitor with oral activity, based on pyrazole and pyrazine structures (IC50 = 2.7 nmol/L) . It effectively inhibits the proliferation of esophageal carcinoma cells and induces apoptosis, making it useful for studying esophageal cancer.

• Smiles:

  ClC=1C=NC=CC1SC2=NNC=3N=C(C=NC23)N4CCC(C)(CN)CC4

• Molecular Formula:

  C17H20ClN7S

• Molecular Weight:

  389.91

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2765183-10-4