TK-642

• Target :

  Phosphatase

• Related Pathways :

  Metabolism

• Bioactivity :

  TK-642 is a potent and selective SHP2 inhibitor with oral activity, based on pyrazole and pyrazine structures (IC50 = 2.7 nmol/L) . It effectively inhibits the proliferation of esophageal carcinoma cells and induces apoptosis, making it useful for studying esophageal cancer.

• Smiles :

  ClC=1C=NC=CC1SC2=NNC=3N=C(C=NC23)N4CCC(C)(CN)CC4

• Molecular Formula :

  C17H20ClN7S

• Molecular Weight :

  389.91

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2765183-10-4