DPP-1-IN-1

• Target:

  Serine Protease|||Proteasome

• Related Pathways:

  Ubiquitination|||Proteases/Proteasome

• Bioactivity:

  DPP-1-IN-1 (Compound 14) is an orally active inhibitor of cathepsin C (also known as dipeptidyl peptidase I), with an IC50 of 5.31 nM. It effectively suppresses downstream neutrophil elastase activity in neutrophils mediated by cathepsin C. DPP-1-IN-1 is applicable for studying inflammatory diseases.

• Smiles:

  FC=1C=C2C=3C(COC2=CC1C[C@H](NC(=O)[C@@H]4CNCCCO4)C#N)=CC(C#N)=CC3

• Molecular Formula:

  C23H21FN4O3

• Molecular Weight:

  420.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2781135-27-9