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DPP-1-IN-1

CAT: 0931-T211142-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211142-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2781135-27-9
Target
Serine Protease, Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome
Bioactivity
DPP-1-IN-1 (Compound 14) is an orally active inhibitor of cathepsin C (also known as dipeptidyl peptidase I), with an IC50 of 5.31 nM. It effectively suppresses downstream neutrophil elastase activity in neutrophils mediated by cathepsin C. DPP-1-IN-1 is applicable for studying inflammatory diseases.
Smiles
FC=1C=C2C=3C(COC2=CC1C[C@H](NC(=O)[C@@H]4CNCCCO4)C#N)=CC(C#N)=CC3
Molecular Formula
C23H21FN4O3
Molecular Weight
420.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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