BMS-986463

• Target :

  Molecular Glues|||Wee1

• Related Pathways :

  PROTAC|||Cell Cycle/Checkpoint

• Bioactivity :

  BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD) . BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC) .

• Smiles :

  O=C1C=2C(CN1[C@@H]3C(=O)NC(=O)CC3)=CC(O[C@@H]4CN(CC5=CC6=C(C(F)=C5)N=C(C=C6)C7CCOCC7)CC4)=CC2

• Molecular Formula :

  C32H33FN4O5

• Molecular Weight :

  572.63

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3025467-07-3