BMS-986458

• Target :

  Bcl-6|||PROTACs

• Related Pathways :

  Immunology/Inflammation|||PROTAC

• Bioactivity :

  BMS-986458 is a highly selective, orally active BCL6 PROTAC degrader. It specifically targets cereblon (CRBN) and the BCL6 N-terminal BTB domain to catalyze proximity-induced BCL6 degradation. BMS-986458 is applicable for research in B-cell non-Hodgkin lymphoma.

• Smiles :

  CN1C=2C(C(=N1)C3C(=O)NC(=O)CC3)=CC=C(N[C@H]4[C@H](C)CN(CC4)C=5N=C(NC=6C=C7C(=CC6)N(C)C(=O)C7)C(Cl)=CN5)C2

• Molecular Formula :

  C32H34ClN9O3

• Molecular Weight :

  628.124

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3005272-36-3