BMS-986458

CAT: 0931-T206353-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206353-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3005272-36-3
Target
Bcl-6|||PROTACs
Related Pathways
Immunology/Inflammation|||PROTAC
Bioactivity
BMS-986458 is a highly selective, orally active BCL6 PROTAC degrader. It specifically targets cereblon (CRBN) and the BCL6 N-terminal BTB domain to catalyze proximity-induced BCL6 degradation. BMS-986458 is applicable for research in B-cell non-Hodgkin lymphoma.
Smiles
CN1C=2C(C(=N1)C3C(=O)NC(=O)CC3)=CC=C(N[C@H]4[C@H](C)CN(CC4)C=5N=C(NC=6C=C7C(=CC6)N(C)C(=O)C7)C(Cl)=CN5)C2
Molecular Formula
C32H34ClN9O3
Molecular Weight
628.124
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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