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BMS-986169

CAT: 0931-T23808-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T23808-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1801151-08-5
Target
Others, NMDAR, iGluR
Related Pathways
Neuroscience, Membrane transporter/Ion channel, Others
Purity
0.9761
Bioactivity
BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, with an IC50 of 24 nM in oocytes, and exhibits antidepressant-like activity in mice, making it a potential treatment for treatment-resistant depression.
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O=C1[C@@H](CCN1CC2=CC=C(C)C=C2)N3C[C@@H](F)[C@@H](CC3)C4=CC=C(O)C=C4
Molecular Formula
C23H27FN2O2
Molecular Weight
382.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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