BMS-986143

• Target:

  Others|||BTK

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis|||Others

• Bioactivity:

  BMS-986143, an orally active, reversible BTK inhibitor with an IC50 value of 0.26 nM, is designed for autoimmune disease research. Additionally, it targets TEC, BLK, BMX, TXK, FGR, YES1, and ITK, exhibiting IC50s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM, 19 nM, and 21 nM, respectively [1].

• Smiles:

  ClC=1C (=C2C (=C (C (N) =O) C1) NC=3C2=CC=C (C (C) (C) O) C3) C4=C (C) C (=CC=C4) N5C (=O) N6C (=CC5=O) C (Cl) =CC=C6

• Molecular Formula:

  C31H24Cl2N4O4

• Molecular Weight:

  587.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1643372-95-5