BMS-986163

• Target:

  NMDAR

• Related Pathways:

  Neuroscience

• Bioactivity:

  BMS-986163 is an effective GluN2B negative allosteric modulator prodrug that converts to the active form BMS-986169 (Ki=4 nM, IC50=24 nM) in vivo, exhibiting antidepressant-like activity in mice.

• Smiles:

  O=C1[C@@H] (CCN1CC2=CC=C (C) C=C2) N3C[C@@H] (F) [C@@H] (CC3) C4=CC=C (OP (=O) (O) O) C=C4

• Molecular Formula:

  C23H28FN2O5P

• Molecular Weight:

  462.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1801151-09-6