WDR5 degrader-1

CAT: 0931-T208803-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T208803-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

3032434-45-7

Target

PROTACs, JAK

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling, Stem Cells, Chromatin/Epigenetic, PROTAC

Bioactivity

WDR5degrader-1 is a cereblon (CRBN) degrader that recruits WDR5. It selectively targets CRBN's new substrate IKZF1 for the degradation of WDR5.

Smiles

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCCCNC(=O)C4=CC(=C(F)C=C4)C5=CC(NC(=O)C=6C(C(F)(F)F)=CC(=O)NC6)=C(C=C5)N7C[C@@H](C)N(C)[C@@H](C)C7)=O

Molecular Formula

C49H52F4N8O9

Molecular Weight

972.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
HY-162014-01	WDR5 degrader-1
HY-168487-01	PROTAC WDR5 degrader 1
BA2863-1	WDR5-IN-1
HY-163774	WDR5-MYC-IN-1
HY-179099	WDR5 probe 1
HY-157659-01	WDR5-MLL1 antagonist 1
PVT39702	pExpress-1-Wdr5 Plasmid
P30588	PExpress-1-Wdr5 (rat)
NBP1-30063CL1	Rabbit Polyclonal WDR5 Antibody [CoraFluor 1]
K2628602	WDR5 sgRNA CRISPR Lentivector (Human) (Target 1)