2-PPA

• Target :

  Potassium Channel|||Others

• Related Pathways :

  Membrane transporter/Ion channel|||Others

• Bioactivity :

  2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 ?M), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.

• Smiles :

  N=1C=CC(N)=CC1C=2C=CC=CC2

• Molecular Formula :

  C11H10N2

• Molecular Weight :

  170.21

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  21203-86-1