2-PPA

CAT: 0931-MF-0056249-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0056249-01Size:10 mg
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CAS Number
21203-86-1
Target
Potassium Channel|||Others
Related Pathways
Membrane transporter/Ion channel|||Others
Bioactivity
2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 ?M), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.
Smiles
N=1C=CC(N)=CC1C=2C=CC=CC2
Molecular Formula
C11H10N2
Molecular Weight
170.21
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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