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2-PPA

CAT: 0931-T89916-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89916-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
21203-86-1
Target
Potassium Channel, Others
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.
Smiles
N=1C=CC(N)=CC1C=2C=CC=CC2
Molecular Formula
C11H10N2
Molecular Weight
170.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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