Products for Research Use Only

2-PPA

CAT: 0013-GTR19237546-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19237546-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-PPA is a selective TMEM175 inhibitor (IC50 = 32 μM) that acutely enhances lysosomal catabolism and macrophage activity. This tool compound is significant for Parkinson's disease research, facilitating studies on lysosomal function in both cellular and animal models.
CAS Number
21203-86-1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.46% (May vary between batches)
Smiles
N=1C=CC (N) =CC1C=2C=CC=CC2
Molecular Formula
C11H10N2
Molecular Weight
170.21
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-Phenylpyridin-4-amine
CAS Number21203-86-1
PubChem CID2762833
IUPAC Name2-phenylpyridin-4-amine
Molecular FormulaC11H10N2
Molecular Weight170.21
XLogP2.1
Topological Polar Surface Area38.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count13
Formal Charge0
Complexity152
SMILES
C1=CC=C(C=C1)C2=NC=CC(=C2)N
InChI
InChI=1S/C11H10N2/c12-10-6-7-13-11(8-10)9-4-2-1-3-5-9/h1-8H,(H2,12,13)
InChIKey
CHVKPWIABFICLK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-Phenylpyridin-4-amine
CAS: 21203-86-1
CID: 2762833
Formula: C11H10N2
MW: 170.21
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight170.21
XLogP32.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass170.084398327
Monoisotopic Mass170.084398327
Topological Polar Surface Area38.9 Ų
Heavy Atom Count13
Formal Charge0
Complexity152
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes