Products for Research Use Only

Nav1.8-IN-16

CAT: 0931-T207225-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207225-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Nav1.8-IN-16 (Compound (R) -40) is an orally bioavailable and selective hNaV 1.8 inhibitor with an IC50 of 5.9 nM. It provides analgesic effects by blocking the NaV1.8 channel without significantly affecting other NaV subtypes or the hERG channel. Nav1.8-IN-16 demonstrates dose-dependent pain relief in postoperative and inflammatory pain models and is suitable for pain-related research.
Molecular Formula
C24H16ClF5N2O3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C