Thalidomide-5- (PEG2-amine)

• Target :

  E3 Ligase Ligand-Linker Conjugate

• Related Pathways :

  PROTAC

• Bioactivity :

  Thalidomide-5- (PEG2-amine) is a Thalidomide analogue that includes an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS esters or carboxylic acids in the presence of EDC or HATU. The PEG spacer enhances water solubility.

• Smiles :

  O=C(NCCOCCOCCN)C1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3

• Molecular Formula :

  C20H24N4O7

• Molecular Weight :

  432.427

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2550398-08-6