Thalidomide-5- (PEG2-amine)

• Description:

  Thalidomide-5- (PEG2-amine) is a PROTAC building block that contains an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS ester group or carboxylic acid in the presence of EDC or HATU. The PEG spacer improves water solubility.

• UNSPSC:

  12352005

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  NCCOCCOCCNC(C1=CC=C2C(N(C(C2=C1)=O)C3CCC(NC3=O)=O)=O)=O

• Molecular Formula:

  C20H24N4O7

• Molecular Weight:

  432.43

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2550398-08-6]