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Thalidomide-O-PEG2-propargyl

CAT: 0931-T18826Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T18826Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2098487-52-4
Target
Others, Autophagy, E3 Ligase Ligand-Linker Conjugate, Apoptosis
Related Pathways
PROTAC, Autophagy, Others, Apoptosis
Bioactivity
Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCOCCOCC#C)C3C2=O)CC1
Molecular Formula
C20H20N2O7
Molecular Weight
400.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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