Thalidomide-5-PEG2-Cl

Thalidomide-5-PEG2-Cl

• CAS Number: 2230956-57-5
• UNSPSC Description: Thalidomide-5-PEG2-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-PEG2-Cl can be connected to the ligand for protein by a linker to form PROTACs[1].
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-5-peg2-cl.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1NC(C(CC1)N2C(C3=CC=C(C=C3C2=O)OCCOCCCl)=O)=O
• Molecular Weight: 380.78
• References & Citations: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-994.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported