Thalidomide-5- (C6-amine)

• Target:

  Ligand for E3 Ligase

• Related Pathways:

  PROTAC

• Bioactivity:

  Thalidomide-5- (C6-amine) is a component of a PROTAC, featuring an E3 ligase ligand substituted with a terminal amine group. This amine group can react with NHS ester groups or carboxylic acids in the presence of either EDC or HATU.

• Smiles:

  O=C(NCCCCCCN)C1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3

• Molecular Formula:

  C20H24N4O5

• Molecular Weight:

  400.428

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1950635-17-2