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(S) -PI3K-IN-2

CAT: 0931-T206641-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206641-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1403458-27-4
Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
(S) -PI3K-IN-2 is the enantiomer of PI3K-IN-2, functioning as a ΡΙ3Κβ/δ inhibitor with IC50 values of 0.198 and 0.282 μM, respectively. It can also inhibit the phosphorylation of AKT (ser473) in MDA-MB-468 cells, with an IC50 of 27 nM.
Smiles
C(=O)(C1=CC(=C2C(=C1)C(=O)C=C(O2)N3CCOCC3)[C@H]4N(CCC4)C5=CC(F)=CC(F)=C5)N6CCOCC6
Molecular Formula
C28H29F2N3O5
Molecular Weight
525.544
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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