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(S) -PI3Kα-IN-4

CAT: 0931-T35488-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T35488-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2322293-84-3
Target
Others, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Others
Bioactivity
(S) -PI3Kα-IN-4, a potent inhibitor of PI3Kα with an IC50 of 2.3 nM, demonstrates 38.3-, 4.25-, and 4.93-fold selectivity over PI3Kβ, PI3Kδ, and PI3Kγ, respectively, and is suitable for cancer research[1]. (S) -PI3Kα-IN-4 (compound 11) is a quinazolin-4 (3H) -one derivative with 2-substituted-N-methylpropanamide substitution[1].
Smiles
CNC(=O)[C@@H](C)Cn1cnc2ccc(cc2c1=O)-c1cnc(OC)c(NS(=O)(=O)c2ccc(F)cc2Cl)c1
Molecular Formula
C25H23ClFN5O5S
Molecular Weight
560
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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