Products for Research Use Only
RegisterLogin

PPARα/γ agonist 3

CAT: 0804-HY-162122Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162122Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PPARα/γ agonist 3 (Compound 4) is a dual agonist of PPARα/γ. PPARα/γ agonist 3 has anti-inflammatory activity, significantly reducing inflammatory markers such as IL-6 and MCP-1 on THP-1 macrophages through NF-κB activation. PPARα/γ agonist 3 can be used in the study of metabolic syndrome and metabolic dysfunction-related fatty liver disease (MAFLD) [1].
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pparα-γ-agonist-3.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(COC2=CC(CCC(C)(CC/C=N/NC3=NC4=C(C=CC=C4)S3)O5)=C5C=C2)C=C1
Molecular Formula
C27H26FN3O2S
Molecular Weight
475.58
References & Citations
[1]García A, et al. Benzopyran hydrazones with dual PPARα/γ or PPARα/δ agonism and an anti-inflammatory effect on human THP-1 macrophages[J]. European Journal of Medicinal Chemistry, 2024: 116125.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-178958PPAR agonist 7
HY-176214PPARγ agonist 19
HY-168719PPARγ agonist 16
HY-162963PPARδ agonist 11
HY-U00340-01PPAR agonist 1
HY-176971PPARα agonist 6
HY-173217PPARα agonist 5
HY-119197-01PPARα/γ/δ agonist 1
HY-163547-01PPAR agonist 5
HY-163443PPAR agonist 4

Alternative Products

CatalogName
T12527-01PPARδ agonist
T210601-01PPARδ agonist 12
T209226-01PPARδ agonist 10
T206860-01PPAR agonist 6
T89149-01PPARα agonist 3
T60535-01PPARα/γ agonist 1
T62266-01PPARα agonist 1
T61417-01PPARγ agonist 7
GTR19241063-01PPARγ agonist 15
GTR19230651-01PPARγ agonist 8

Popular Products