HDAC-IN-84

• Target:

  Apoptosis|||HDAC

• Related Pathways:

  DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic

• Bioactivity:

  HDAC-IN-84 (compound 4a) is a potent HDAC inhibitor with IC50 values of 0.0045, 0.015, 0.013, 0.038, 5.8, and 26 ?M for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC11, respectively. It effectively inhibits the proliferation of leukemia cells without causing toxicity.

• Smiles:

  COC1=CC=C (C=C1) C2=CSC (=N2) C (=O) NOCCCCCC (=O) NO

• Molecular Formula:

  C17H21N3O5S

• Molecular Weight:

  379.431

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C