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HDAC-IN-83

CAT: 0931-T203648-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T203648-01Size: 10 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
HDAC
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
HDAC-IN-83 (compound 9D) is an inhibitor of histone deacetylase (HDAC), demonstrating an IC50 of 0.01 ?M for HDAC1 and 0.44 ?M for HDAC6. It exhibits anticancer and antiproliferative activities and promotes caspase-3/7 activation. The compound inhibits Cal27, HepG2, and MRC-5 cells with IC50 values of 0.693 ?M, 0.427 ?M, and 3.19 ?M, respectively.
Molecular Formula
C29H40N6O4
Molecular Weight
536.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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