Ro 44-3888

CAT: 0931-T202774-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T202774-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

144412-18-0

Bioactivity

Ro 44-3888, the active component of sibrafiban, achieves predictable plasma concentrations when administered orally in its prodrug form, Ro 48-3657. Upon reaching a steady state after the second dose, Ro 44-3888 exhibits concentration-dependent inhibition of platelet aggregation and prolongs bleeding time. These findings suggest that Ro 44-3888 merits further evaluation, especially in patients at high risk of arterial thrombosis and those with acute coronary syndrome, due to its reliable absorption.

Smiles

C(N[C@H](C(=O)N1CCC(OCC(O)=O)CC1)C)(=O)C2=CC=C(C(=N)N)C=C2

Molecular Formula

C18H24N4O5

Molecular Weight

376.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Ro 44-3888

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