RO-5963

• Target:

  MDM-2/p53|||E1/E2/E3 Enzyme|||Mdm2|||p53

• Related Pathways:

  Apoptosis|||Ubiquitination

• Purity:

  0.9936

• Bioactivity:

  RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively) .

• Smiles:

  C(C(NC(CO)CO)=O)(N1C(=O)C(=CC=2C=3C(NC2)=C(C)C(Cl)=CC3)NC1=O)C4=CC(F)=C(F)C=C4

• Molecular Formula:

  C24H21ClF2N4O5

• Molecular Weight:

  518.9

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1416663-77-8