RO-5963

• Target :

  MDM-2/p53|||E1/E2/E3 Enzyme|||Mdm2|||p53

• Related Pathways :

  Apoptosis|||Ubiquitination

• Purity :

  0.9936

• Bioactivity :

  RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively) .

• Smiles :

  C(C(NC(CO)CO)=O)(N1C(=O)C(=CC=2C=3C(NC2)=C(C)C(Cl)=CC3)NC1=O)C4=CC(F)=C(F)C=C4

• Molecular Formula :

  C24H21ClF2N4O5

• Molecular Weight :

  518.9

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1416663-77-8