CDK2-IN-44

• Description :

  CDK2-IN-44 (Compound 46) is an inhibitor of cyclin-dependent kinase 2 (CDK2) . CDK2-IN-44 can effectively inhibit the proliferation of cancer cells and exert its activity in inhibiting cancer cell growth by arresting the cell cycle, promoting Apoptosis, and inducing cellular senescence. CDK2-IN-44 holds promise for use in the research of ovarian cancer and breast cancer[1].

• UNSPSC :

  12352005

• Target :

  CDK

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Smiles :

  FC1=CC(C2=NC(NC3CCN(S(=O)(C4CC4)=O)CC3)=NC=C2F)=CN(C(CC)C)C1=O

• Molecular Formula :

  C21H27F2N5O3S

• Molecular Weight :

  467.53

• References & Citations :

  [1]Chen W, et al. Discovery of potent and selective CDK2 inhibitors with high safety and favorable bioavailability for the treatment of cancer. Eur J Med Chem. 2025 Jun 5;290:117503.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDK2

• CAS Number :

  [3051587-93-7]