RO 4938581

• Target:

  GABA Receptor

• Related Pathways:

  Membrane transporter/Ion channel|||Neuroscience

• Bioactivity:

  RO 4938581 is an effective and selective agonist of GABAA ?5 inverse (Ki: 4.6 nM for GABAA ?5?3?2a, and shows a lower affinity at ?1?3?2a, ?2?3?2a, ?3?3?2a (Ki, 174, 185, 80 nM, respectively) ) .

• Smiles:

  FC(F)c1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21

• Molecular Formula:

  C13H8BrF2N5

• Molecular Weight:

  352.14

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  883093-10-5