Ro 5126766

• Target :

  Raf|||MEK

• Related Pathways :

  MAPK

• Purity :

  0.9881

• Bioactivity :

  RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.

• Smiles :

  CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F

• Molecular Formula :

  C21H18FN5O5S

• Molecular Weight :

  471.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  946128-88-7