Ro 5126766

• Target:

  Raf|||MEK

• Related Pathways:

  MAPK

• Purity:

  0.9881

• Bioactivity:

  RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.

• Smiles:

  CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F

• Molecular Formula:

  C21H18FN5O5S

• Molecular Weight:

  471.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  946128-88-7