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PROTAC SMARCA2 degrader-28

CAT: 0931-T201699-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201699-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2641510-88-3
Target
PROTACs, Epigenetic Reader Domain
Related Pathways
PROTAC, Chromatin/Epigenetic
Bioactivity
PROTAC SMARCA2 degrader-28 (Compound 158) is a potent SMARCA2 PROTAC degrader that achieves degradation of SMARCA2 in HiBiT A549 cells, exhibiting a DC50 of 3 nM.
Smiles
O=C(C(F)(F)F)O.O=C1C2=CC=C(N3CCC(CC3)C(N4CCN(CC4)CC5=CC(N6C7CN(CC6CC7)C8=C(N)N=NC(C9=CC(F)=CC=C9O)=C8)=CC=C5)=O)C=C2C(N1C%10C(NC(CC%10)=O)=O)=O.O=C(C(F)(F)F)O
Molecular Formula
C50H51F7N10O10
Molecular Weight
1084.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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