Hexanorcucurbitacin D

• Description :

  Hexanorcucurbitacin D, a cucurbitacin, is a weak ecdysteroid receptor agonist. Hexanorcucurbitacin D can be isolated from Trichosanthes cucumeroides roots. Hexanorcucurbitacin D can be used for the research of cardiovascular disease (CVD) [1][2].

• CAS Number :

  [29065-05-2]

• UNSPSC :

  12352211

• Target :

  FXR

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/hexanorcucurbitacin-d.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC([C@H]1[C@@H](C[C@]2([C@@H]3CC=C4[C@H]([C@@]3(C(C[C@]12C)=O)C)C[C@@H](C(C4(C)C)=O)O)C)O)=O

• Molecular Formula :

  C24H34O5

• Molecular Weight :

  402.52

• References & Citations :

  [1]Xianjing Zhang, et al. Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives. J Nat Prod. 2020 Dec 24;83 (12) :3536-3544.|[2]L Dinan, et al. Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor. Biochem J. 1997 Nov 1;327 (Pt 3) (Pt 3) :643-50.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported