Hexanorcucurbitacin D

Hexanorcucurbitacin D

• CAS Number: 29065-05-2
• UNSPSC Description: Hexanorcucurbitacin D, a cucurbitacin, is a weak ecdysteroid receptor agonist. Hexanorcucurbitacin D can be isolated from Trichosanthes cucumeroides roots. Hexanorcucurbitacin D can be used for the research of cardiovascular disease (CVD)[1][2].
• Target Antigen: FXR
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/hexanorcucurbitacin-d.html
• Solubility: 10 mM in DMSO
• Smiles: CC([C@H]1[C@@H](C[C@]2([C@@H]3CC=C4[C@H]([C@@]3(C(C[C@]12C)=O)C)C[C@@H](C(C4(C)C)=O)O)C)O)=O
• Molecular Weight: 402.52
• References & Citations: [1]Xianjing Zhang, et al. Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives. J Nat Prod. 2020 Dec 24;83(12):3536-3544.|[2]L Dinan, et al. Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor. Biochem J. 1997 Nov 1;327 ( Pt 3)(Pt 3):643-50.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported