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7α,24 (S) -Dihydroxycholesterol

CAT: 0931-T200871-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T200871-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
245523-67-5
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
7α,24 (S) -Dihydroxycholesterol ((3β,7α,24S) -Cholest-5-ene-3,7,24-triol) acts as a ligand for liver X receptors (LXR), specifically binding to the ligand-binding domains of LXRα and LXRβ. This compound is synthesized through the E-α, β-unsaturated ketone process, starting with arsindole and J-secondary-butyl dimethylsiloxy-bis-positive-5-cholestenal as the initial materials. It undergoes a series of transformations to produce 7α,24 (S) -dihydroxycholesterol.
Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=C[C@H]3O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@@H](C(C)C)O)C)[H])[H]
Molecular Formula
C27H46O3
Molecular Weight
418.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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