7α,25-Dihydroxycholesterol

• Description:

  7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183) . 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  418.65

• Molecular Formula:

  C27H46O3

• Notes:

  Research use only, not for human use.

• Receptor:

  Human Endogenous Metabolite|GPR183

• CAS Number:

  64907-22-8