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7α,25-Dihydroxycholesterol

CAT: 1410-M22488-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M22488-01Size:1 g
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Description
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183) . 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM) .
CAS Number
64907-22-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
418.65
Molecular Formula
C27H46O3
Notes
Research use only, not for human use.
Receptor
Human Endogenous Metabolite|GPR183

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