PARP1/BRD4-IN-3

CAT: 0931-T200653-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T200653-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

DNA/RNA Synthesis, Apoptosis, Epigenetic Reader Domain, PARP

Related Pathways

Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis

Bioactivity

PARP1/BRD4-IN-3 (compound HF4) is an effective inhibitor of BRD4 and PARP1, with IC50 values of 1210 nM and 2019 nM respectively. The compound exhibits antiproliferative activity, induces apoptosis (apoptosis) and cell cycle arrest at the G0/G1 phase. Additionally, PARP1/BRD4-IN-3 causes DNA damage and reduces the expression of the Rad51 protein, demonstrating anti-tumor activity.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T209282-01	BRD4-BD1-IN-3
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T89841-01	PROTAC BRD4 ligand-3
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Alternative Products

Catalog	Name
HY-169170	PARP1/BRD4-IN-3
HY-150613	PARP1/BRD4-IN-2
GTR19185181-01	PARP1/BRD4-IN-1
HY-104072	BRD4-IN-3
MBS5780213	BRD4-Kinases-IN-3
HY-136857-01	BRD4 degrader-3
GTR19234227-01	PLK1/BRD4-IN-3
GTR19261923-01	BRD4-BD1-IN-3
GTR19274866-01	BRD4 D1-IN-3
HY-163817	PARP1/2-IN-3

PARP1/BRD4-IN-3

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