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BRD4-BD1/2-IN-3

CAT: 0931-T210452-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T210452-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3106588-54-6
Target
Epigenetic Reader Domain, Others
Related Pathways
Others, Chromatin/Epigenetic
Purity
0.9963
Bioactivity
BRD4-BD1/2-IN-3 is a highly selective BRD4 BD2 inhibitor (IC50 = 0.41 nM) that exhibits strong selectivity over BRD4 BD1 and potently suppresses LPS-induced IL-6 expression. BRD4-BD1/2-IN-3 modulates TNF and NF-κB signaling pathways, providing a valuable tool for studying BRD4 biology and for researches on inflammatory diseases.
Smiles
O=C1N=C(NC=2C=C(OC)C=C(OC)C12)C=3C=NN(C3)CC=4C=CC=CC4
Molecular Formula
C20H18N4O3
Molecular Weight
362.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C