CBI1 formic

CAT:
931-T200596-01
Size:
10 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
CBI1 formic - image 1

CBI1 formic

  • Target :

    Bcl-2 Family
  • Related Pathways :

    Apoptosis
  • Bioactivity :

    CBI1 formic is a covalent inhibitor of BAX, selectively derivatizing BAX at C126 and inhibiting its activation by triggering with a ligand or point mutation. This compound effectively blocks the t-2-hex lipidation and oligomerization of BAX. Additionally, CBI1 formic inhibits BAX activation induced by BH3 ligands, F116A mutations, or t-2-hex.
  • Shipping Conditions :

    Cool pack
  • Storage Temperature :

    -20°C

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