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CBI1 formic

CAT: 0931-T200596-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200596-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Bcl-2 Family
Related Pathways
Apoptosis
Bioactivity
CBI1 formic is a covalent inhibitor of BAX, selectively derivatizing BAX at C126 and inhibiting its activation by triggering with a ligand or point mutation. This compound effectively blocks the t-2-hex lipidation and oligomerization of BAX. Additionally, CBI1 formic inhibits BAX activation induced by BH3 ligands, F116A mutations, or t-2-hex.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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