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CBI1

CAT: 0931-T209057-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209057-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Bcl-2 Family
Related Pathways
Apoptosis
Bioactivity
CBI1 is a covalent BAX inhibitor. It selectively derivatizes BAX at C126 and inhibits BAX activation by triggering a ligand or through point mutations. CBI1 prevents the lipidation and oligomerization of BAX by t-2-hex. It also inhibits BAX activation induced by BH3 ligands, F116A mutation, or t-2-hex.
Smiles
BrC1=CC=C(C2=NNC(C(NCCCSSCCN)=O)=C2)C=C1
Molecular Formula
C15H19BrN4OS2
Molecular Weight
415.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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