Nampt-IN-3

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

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Nampt-IN-3

CAT:

804-HY-108701-04

Size:

25 mg

Price:

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For price, please contact [email protected].

CAS Number: 2121591-52-2
UNSPSC Description: Nampt-IN-3 (Compound 35) simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. Nampt-IN-3 effectively induces cell apoptosis and autophagy and ultimately leads to cell death[1].
Target Antigen: Apoptosis; Autophagy; HDAC; NAMPT
Type: Reference compound
Related Pathways: Apoptosis;Autophagy;Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/nampt-in-3.html
Purity: 98.97
Solubility: DMSO : 130 mg/mL (ultrasonic)
Smiles: O=C(C1=CC=C(C2=CN(CC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3)N=N2)C=C1)NCC5=CC=CN=C5
Molecular Weight: 503.55
References & Citations: [1]Dong G, et al. Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors. J Med Chem. 2017 Oct 12;60(19):7965-7983.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

Complementary Product Range

Our range of products, including Nampt-IN-3, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

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Find us on

Cat	Name
HY-108701-06	Nampt-IN-3
HY-108701-05	Nampt-IN-3
HY-108701-04	Nampt-IN-3
HY-108701-03	Nampt-IN-3
HY-108701-01	Nampt-IN-3
HY-108701-02	Nampt-IN-3
HY-164759	Nampt-IN-13
HY-161712-05	Nampt-IN-12
HY-161712-04	Nampt-IN-12
HY-161712-02	Nampt-IN-12