Nampt-IN-7

CAT: 0804-HY-147756Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147756Size:1 Each
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Description
Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].
CAS Number
[1223378-42-4]
UNSPSC
12352005
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nampt-in-7.html
Solubility
10 mM in DMSO
Smiles
CCOC(C1=CC=C(C=C1)NC(NCC2=CC(N3C=CN=C3C)=NC=C2)=O)=O
Molecular Formula
C20H21N5O3
Molecular Weight
379.41
References & Citations
[1]Ozgencil F, et al. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. Bioorg Med Chem. 2020 Jan 1;28 (1) :115217.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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