B Raf Rabbit mAb

CAT: 0866-RDSA66648Size: 100 µLDry Ice: NoHazardous: No
CAT#:0866-RDSA66648Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations.
Description
This is a B Raf Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
B-RAF; p94; NS7; B-Raf proto-oncogene serine/threonine-protein kinase; BRAF; BRAF1
Swiss Prot
P15056
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human B Raf
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, IP, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, IP 1:50, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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