B-Raf Polyclonal Antibody

• Background :

  This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

• Description :

  This is a B-Raf Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  BRAF, B-RAF1, B-raf, BRAF1, NS7, RAFB1, serine/threonine-protein kinase B-raf

• Gene ID :

  673

• Swiss Prot :

  P15056

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human B-Raf

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  89kDa

• Observed Molecular Weight :

  92KDa

• Host or Source :

  Rabbit

• Isotype :

  IgG