B-Raf Polyclonal Antibody

• Background:

  This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

• Description:

  This is a B-Raf Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BRAF, B-RAF1, B-raf, BRAF1, NS7, RAFB1

• Gene ID:

  673

• Swiss Prot:

  P15056

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human B-Raf

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  49kDa

• Observed Molecular Weight:

  50KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG