PI3KCD Antibody

• Background:

  Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha , p110-beta, and p110-gamma. p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins and with GTP-bound Ras.

• NCBI Gene ID:

  5293

• Swiss Prot:

  O00329

• Accession Number:

  O00329

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PI3KCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human PI3KCD.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  119 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PIK3CD

• NCBI Official Name:

  Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Khan, N.A., et al., J. Neurovirol. 9 (6) :584-593 (2003) .

• Background Reference 02:

  Sadhu, C., et al., J. Immunol. 170 (5) :2647-2654 (2003) .

• Background Reference 03:

  Deregibus, M.C., et al., J. Biol. Chem. 277 (28) :25195-25202 (2002) .

• Background Reference 04:

  Cook, J.A., et al., J. Immunol. 169 (1) :254-260 (2002) .

• Other Product Names:

  Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PtdIns-3-kinase subunit delta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, PIK3CD

• Tested Applications:

  WB, IHC-P, IF

• Physical Properties:

  Liquid