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PI3KCD Antibody

CAT: 0223-63-347Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-347Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha , p110-beta, and p110-gamma. p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins and with GTP-bound Ras.
NCBI Gene ID
5293
Swiss Prot
O00329
Accession Number
O00329
Host
Rabbit
Reactivity
Human
Immunogen
This PI3KCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human PI3KCD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
119 kDa
Fragment
Rabbit Ig
Symbol
PIK3CD
NCBI Official Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
NCBI Organism
Homo sapiens
Background Reference 01
Khan, N.A., et al., J. Neurovirol. 9 (6) :584-593 (2003) .
Background Reference 02
Sadhu, C., et al., J. Immunol. 170 (5) :2647-2654 (2003) .
Background Reference 03
Deregibus, M.C., et al., J. Biol. Chem. 277 (28) :25195-25202 (2002) .
Background Reference 04
Cook, J.A., et al., J. Immunol. 169 (1) :254-260 (2002) .
Other Product Names
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PtdIns-3-kinase subunit delta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, PIK3CD
Tested Applications
WB, IHC-P, IF
Physical Properties
Liquid

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