PI3KCD Antibody (C-term) [APR32533G]

• Background:

  Tissue Location: In humans, the highest levels of expression are seen in peripheral blood mononuclear cells, spleen, and thymus, and low levels of expression in testes, uterus, colon, and small intestine but not in other tissues examined including prostate, heart, brain, and liver (PubMed:9235916) . Isoform 2 is expressed in normal thymus, lung and spleen tissues, and is detected at low levels in normal lysates from colon and ovarian biopsies, at elevated levels in lysates from colorectal tumors and is abundantly expressed in some ovarian tumors (at protein level) . Both isoform 1 and isoform 2 are widely expressed Isoform 1 is expressed predominantly in leukocytes

• Synonyms:

  Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PtdIns-3-kinase subunit delta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, PIK3CD

• Gene Name:

  PIK3CD

• Gene ID:

  5293

• UniProt:

  O00329

• Chromosomal Location:

  Cytoplasm.

• Applications:

  IF, WB, IHC-P-Leica

• Dilution:

  IHC-P-Leica--1:500 WB--1:2000 IF--1:10~50

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  923591615135396

• Molecular Weight:

  119479

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PI3KCD Antibody (C-term) [APR32533G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5293

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00329