PI3KR2 Antibody

• Background:

  PI3KR2 binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.

• NCBI Gene ID:

  5296

• Swiss Prot:

  O00459

• Accession Number:

  O00459

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PI3KR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-298 amino acids from the C-terminal region of human PI3KR2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  82 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PIK3R2

• NCBI Official Name:

  Phosphatidylinositol 3-kinase regulatory subunit beta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Janssen, J.W., et al., Oncogene 16 (13) :1767-1772 (1998) .

• Background Reference 02:

  Volinia, S., et al., Oncogene 7 (4) :789-793 (1992) .

• Background Reference 03:

  Carpenter, C.L., et al., J. Biol. Chem. 265 (32) :19704-19711 (1990) .

• Other Product Names:

  Phosphatidylinositol 3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, PtdIns-3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PI3-kinase subunit p85-beta, PtdIns-3-kinase regulatory subunit p85-beta, PIK3R2

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid