MAP4K1 Antibody

CAT: 0223-63-315Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-315Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAP4K1 or HPKI (hematopoietic progenitor kinase I) is one of these mammalian kinases that have significant sequence similarity to the Saccharomyces Cerevisiae serine/threonine kinase STE20, which relays signals from G protein coupled receptors to cytosolic MAP kinase cascades. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N terminal pathway. It may play a role in hematopoietic lineage decisions and growth regulation.
NCBI Gene ID
11184
Swiss Prot
Q92918
Accession Number
Q92918
Host
Rabbit
Reactivity
Human
Immunogen
This MAP4K1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from human MAP4K1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
91 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MAP4K1
NCBI Official Name
Mitogen-activated protein kinase kinase kinase kinase 1
NCBI Organism
Homo sapiens
Background Reference 01
Hu M.C.-T., Genes Dev. 10:2251-2264 (1996) .
Background Reference 02
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135 (2004) .
Background Reference 03
Wissing J., Mol. Cell. Proteomics 6:537-547 (2007) .
Other Product Names
Mitogen-activated protein kinase kinase kinase kinase 1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEKKK 1, MAP4K1, HPK1
Tested Applications
WB
Protein ID
29427916
Physical Properties
Liquid

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