MAPK1 Antibody

CAT: 0223-XW-7183Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-XW-7183Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitogen-activated protein kinase 1; extracellular signal-regulated kinase 2; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2. This protein is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
NCBI Gene ID
5594
Swiss Prot
P28482
Accession Number
NP_620407.1
Host
Chicken
Reactivity
Human, Mouse, Rat
Immunogen
232-360
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Cancer
Purification
Antigen affinity-purified
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MAPK1 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41.3 kDa (calculated)
Applications Notes
ERK2 antibody can be used for the detection of ERK2 by Western blot, may also work for IHC and ICC.
Symbol
MAPK1
NCBI Official Name
Mitogen-activated protein kinase 1
NCBI Organism
Homo sapiens
Background Reference 01
Bhalla, U. S., Ram, P. T., Iyengar, R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297: 1018-1023, 2002.
Other Product Names
ERK2, PRKM1, PRKM2, Mitogen-activated protein kinase 1, ERT1, MAP kinase 1, ERK, p38, p40, p41, ERK2, ERK-2, MAPK2, P42MAPK, p41mapk, p42-MAPK
Tested Applications
WB
Protein ID
20986531
Physical Properties
Liquid

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