MAP3K1 Antibody

• Background:

  MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin (MIM 176730) and many growth factors.MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin (MIM 176730) and many growth factors.

• NCBI Gene ID:

  4214

• Swiss Prot:

  Q13233

• Accession Number:

  NP_005912

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP3K1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MAP3K1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  164 kDa

• Applications Notes:

  MAP3K1 antibody can be used for detection of MAP3K1 by ELISA at 1:312500. MAP3K1 antibody can be used for detection of MAP3K1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MAP3K1

• NCBI Official Name:

  Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hancock, L., (er) Inflamm. Bowel Dis. (2008) In press.

• Other Product Names:

  MAP3K1, MAPKKK1, MEKK, MEKK1, SRXY6, MEKK 1

• Tested Applications:

  ELISA, WB

• Protein ID:

  153945765

• Physical Properties:

  Liquid