MAP4K5 Antibody

• Background:

  This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

• NCBI Gene ID:

  11183

• Swiss Prot:

  Q9Y4K4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 300-480 of human MAP4K5 (NP_006566.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 120kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  MAP4K5

• Positive Control 2:

  A-549

• Positive Control 3:

  Jurkat

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Mouse spleen

• Positive Control 6:

  Rat brain

• NCBI Official Name:

  Mitogen-activated protein kinase kinase kinase kinase 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GCKR, KHS, KHS1, MAPKKKK5, mitogen-activated protein kinase kinase kinase kinase 5, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, MEKKK 5, germinal center kinase-related, kinase homologous to SPS1/STE20

• Tested Applications:

  WB

• Physical Properties:

  Liquid