MAP4K2 Antibody

CAT: 223-26-330Size: 100 µLDry Ice: NoHazardous: No
100 µLSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
NCBI Gene ID
5871
Swiss Prot
Q12851
Accession Number
NP_004570
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP4K2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MAP4K2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
91 kDa
Applications Notes
MAP4K2 antibody can be used for detection of MAP4K2 by ELISA at 1:312500. MAP4K2 antibody can be used for detection of MAP4K2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MAP4K2
NCBI Official Name
Mitogen-activated protein kinase kinase kinase kinase 2
NCBI Organism
Homo sapiens
Background Reference 01
Wissing, J., (2007) Mol. Cell Proteomics 6 (3), 537-547.
Other Product Names
MAP4K2, BL44, GCK, RAB8IP
Tested Applications
ELISA, WB
Protein ID
22035600
Physical Properties
Liquid