Mouse Txnip Antibody

CAT: 0223-60-886Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-886Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
NCBI Gene ID
56338
Swiss Prot
Q8BG60
Accession Number
Q8BG60
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Txnip
NCBI Official Name
Thioredoxin-interacting protein
NCBI Organism
Mus musculus
Background Reference 01
Kwon, H.J., et al. Toxicol. Appl. Pharmacol. 248 (3) :277-284 (2010)
Background Reference 02
Kwon, H.J., et al. J. Immunol. 185 (7) :3980-3989 (2010)
Background Reference 03
Ren, Y., et al. FEBS Lett. 584 (15) :3480-3485 (2010)
Background Reference 04
Chutkow, W.A., et al. Diabetes 59 (6) :1424-1434 (2010)
Other Product Names
Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1
Tested Applications
WB
Physical Properties
Liquid

Related Products

CatalogName
33-035TXNIP Antibody
7941-01mgTXNIP Antibody
7941-01TXNIP Antibody
7941-002mgTXNIP Antibody
7941PTXNIP Peptide
56-272Mouse Parp9 Antibody
57-277Mouse Acvr1 Antibody
57-279Mouse Camk2d Antibody
55-291Mouse Dnmt2 Antibody
55-295Mouse Dnmt3L Antibody

Alternative Products

CatalogName
abx031399-01Mouse Txnip Antibody
E45R31914G-4Mouse Txnip Antibody (Center)
P0408Human, Rat, Mouse TXNIP antibody
NBP1-54578SSMouse Monoclonal TXNIP Antibody (JY2)
E10G34777Mouse Txnip Rabbit Polyclonal Antibody
APR31914G-01Mouse Txnip Antibody (Center) [APR31914G]
NBP1-54578HMouse Monoclonal TXNIP Antibody (JY2) [HRP]
NBP1-54578FMouse Monoclonal TXNIP Antibody (JY2) [FITC]
NBP1-54578PEMouse Monoclonal TXNIP Antibody (JY2) [PE]
NBP1-54578APCMouse Monoclonal TXNIP Antibody (JY2) [Allophycocyanin]

Popular Products