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Mouse Acvr1 Antibody

CAT: 0223-57-277Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-277Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.
NCBI Gene ID
11477
Swiss Prot
P37172
Accession Number
P37172
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Acvr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the Central region of mouse Acvr1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
Acvr1
NCBI Official Name
Activin receptor type-1
NCBI Organism
Mus musculus
Background Reference 01
Luo, J., et al. J. Biol. Chem. 285 (38) :29588-29598 (2010)
Background Reference 02
Song, G.A., et al. J. Biol. Chem. 285 (29) :22542-22553 (2010)
Background Reference 03
Shimogori, T., et al. Nat. Neurosci. 13 (6) :767-775 (2010)
Background Reference 04
Suzuki, Y., et al. J. Cell. Sci. 123 (PT 10), 1684-1692 (2010) :
Other Product Names
Activin receptor type-1, Activin receptor type I, ACTR-I, Serine/threonine-protein kinase receptor R1, SKR1, TGF-B superfamily receptor type I, TSR-I, TSK-7L, Acvr1, Acvrlk2, Tgfb1
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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